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Safety,Applicability and Efficacy Test of Cosmetics in China

 

1. Chemical tests:

l          Heavy metals: lead, arsenic, mercury, cadmium, chromium, zirconium, neodymium, beryllium, antimony, thallium, strontium, selenium and so on.

l          Components for hair: mercaptoacetic acid, selenium disulfide.

l          Preservatives: Nipagin esters, phenoxy ethanol, benzyl alcohol, salicylic acid, sorbic acid, formaldehyde, acetic acid dehydrogenation, dichlorobenzyl methanol, boric acid, benzoic acid, benzoyl peroxide, etc.

l          Sex hormones: estradiol, estriol, diethylstilbestrol, testosterone, methyl testosterone, progesterone.

l          Sun-screening agent: phenyl benzimidazole sulfonic acid, benzophenone-4 and benzophenone -5, p-aminobenzoic acid, diphenyl ketone -3, p-methoxy cinnamic acid isoamyl ester, 4-ethylbezilidene camphor, PABA ethylhexyl ester, Butyl methoxydibenzoylmethane, Octocrylene, methoxy-cinnamic acid ethylhexyl ester, salicylic acid ethylhexyl ester, homosalate, ethylhexyl triazone, methylenebis-Benzotriazole -4-methyl-phenol), bisethylhexyl phenol methoxyphenyl triazone.

l          Hair dying agent: p-phenylene diamine, hydroquinone, m-amino-phenol, o--phenylenediamine, p-aminophenol, toluene 2,5 - diamine, resorcinol, p-methylaminophenol.

l          |á-hydroxy acids: tartaric acid, glycolic acid, malic acid, lactic acid, citric acid.

l          Antibiotics: dihydrate oxytetracycline, tetracycline hydrochloride, chlortetracycline hydrochloride, chloramphenicol and metronidazole.

l          Vitamins: vitamin D2, vitamin D3, vitamin E and acetates

 

2. Microbial Test

l          Total bacteria count,

l          fecal coliform,

l          Staphylococcus aureus,

l          Pseudomonas aeruginosa,

l          Shigella,

l          Pseudomonas aeruginosa,

l          Mold and yeast.

3. Animal Test (in accordance with Hygienic Standard for Cosmetics):

l          Acute oral toxicity test

l          Acute percutaneous toxicity test

l          Acute and repeated skin irritation / corrosion test

l          Acute eye irritation / corrosion test

l          Skin hypersensitivity / allergy test

l          Skin phototoxicity test

l          Sub-chronic percutaneous toxicity test

 

4. Animal substitution test (In accordance with OECD, the industry standards of EU and inspection and quarantine):

l          3T3 neutral red absorption phototoxicity test

l          Acute keratinocyte toxicity test

l          Acute 3T3 cell toxicity test

l          Hen's egg test-chorioallantoic membrane test for eye irritation / corrosion test

l          Stem cell test for embryo and developmental toxicity

 

5. Applicability and Efficacy Tests

l          Human skin patch test (deodorant category / sunscreen category / spot-dispelling category)

l          Cosmetics SPF determination (human test)

l          Cosmetics SPA determination (human test)

l          Waterproof property test of sunscreen cosmetics (human test)

l          Efficacy evaluation on moisturizing cosmetics

l          Efficacy evaluation on anti-fat cosmetics

l          Efficacy evaluation on anti-wrinkle cosmetics

l          Efficacy evaluation on whitening cosmetics

 

 

 

 

 

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Important Note
Due to the reorganization of the Chinese government in 2018,
CFDA (China Food and Drug Administration) was renamed to NMPA (National Medical Product Administration), and its food supervision function has been transferred to SAMR (State Administration for Market Regulation of China);
GACC (General Administration of Quality Supervision, Inspection and Quarantine of China) was abolished, and its import and export trade supervision function has been transferred to GACC (General Administration of Customs of China),
Therefore, all
CFDA and SFDA on this website default to NMPA, GACC defaults to GACC; 
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